September 7, 2013

Heart transplantation outcomes from cardiac arrest-resuscitated donors.


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

CPR requiring donors, utilized and identified in the UNOS database tended to be younger and had a mean CPR time of 20 minutes. Despite resucitation times, use of carefully selected donors requiring CPR did not impact recipient outcomes including patient and graft survival. The authors hypothesize that ischemic preconditioning may influence the non-inferior outcomes.

Leave a Comment! Posted in Cardiac Transplantation Tags: , , , , ,
September 2, 2013

Influence of Race/Ethnic Differences in Pre-Transplant Panel Reactive Antibody on Outcomes in Heart Transplant Recipients.


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Racial and ethnic differences in long-term survival after HT are well recognized. This US study demonstrated that after adjusting for BMI, blood type, sensitization, presence of VAD at transplant, and region, both Black and Hispanic race/ethnicity ( β=0.046, p

Leave a Comment! Posted in Cardiac Transplantation Tags: , , , , ,
September 1, 2013

Podocyte Effacement Closely Links to suPAR Levels at Time of Posttransplantation Focal Segmental Glomerulosclerosis Occurrence and Improves With Therapy


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Serum soluble urokinase-type plasminogen activator receptor (suPAR) has been put forth as the a candidate for the elusive “FSGS” factor that may lead to aggressive and early recurrence post-transplant. This study of patients with recurrent FSGS post-transplant found higher suPAR levels in patients with more extensive podocyte damage on renal biopsy. However, this study is […]

Leave a Comment! Posted in Renal Transplantation Tags: , , , , ,
August 31, 2013

Higher Risk of Kidney Graft Failure in the Presence of Anti-Angiotensin II Type-1 Receptor Antibodies


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

While HLA antibodies are a well-recognized risk factor for graft loss, the role of non-HLA antibodies is less clear. Antibodies to angiotensin II type I receptor has been previously reported in patients with failing grafts. In this study, patients who developed anti-AT I receptor antibodies had a higher risk of graft failure over and above […]

Leave a Comment! Posted in Renal Transplantation, Uncategorized Tags: , , , ,
August 30, 2013

Improving Outcomes of Renal Transplant Recipients With Behavioral Adherence Contracts: A Randomized Controlled Trial


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Non-adherence is a well-recognized risk factor for adverse events post-transplant, but there have been few interventions aimed at improving adherence. In this randomized controlled trial, regular interaction with a pharmacist and a contract laying out behaviours required of the patient improved adherence, as measured by medication refills. It also resulted in fewer hospitalization.

Leave a Comment! Posted in Renal Transplantation, Uncategorized Tags: , , , , , , ,
August 2, 2013

Urinary-Cell mRNA Profile and Acute Cellular Rejection in Kidney Allografts


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

The gold standard fro diagnosing acute rejection remains biopsy. A non-invasive test that could reliably diagnose rejection would be an important step forward. In this study, a set of three different RNA molecules in the urine of renal transplant recipients showed a high degree of sensitivity for acute cellular rejection, and distinguished it from antibody-mediated […]

Leave a Comment! Posted in Renal Transplantation Tags: , , , , , , ,
July 11, 2013

HeartWare ventricular assist system for bridge to transplant: Combined results of the bridge to transplant and continued access protocol trial.


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

The pivotal ADVANCE Clinical Trial was a multicenter clinical trial to evaluate the HeartWare HVAD System for BTT in patients with advanced heart failure in the United States. This publication reports the analysis of combined data from the 140 BTT patients plus 192 patients from the continued access protocol (CAP) who were monitored to outcome […]

Leave a Comment! Posted in Cardiac Transplantation Tags: , , , ,
July 10, 2013

A cardioprotective preservation strategy employing ex vivo heart perfusion facilitates successful transplant of donor hearts after cardiocirculatory death.


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Various techniques are being explored to optimize hearts and the assess organ function before transplantation. This may ultimately increase the number of organs available for transplantation. In this experimental model of DCD, an ex vivo heart perfusion strategy using initial reperfusion with a tepid adenosine-lidocaine cardioplegia and continuous myocardial perfusion minimized myocardial injury and improved […]

Leave a Comment! Posted in Cardiac Transplantation Tags: , , , , , ,
July 9, 2013

Prophylactic implantable cardioverter defibrillator treatment in patients with end-stage heart failure awaiting heart transplantation.


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

This observational study supports the CCS recommendations of ICD consideration in transplant eligible patients. In this study, ICDs appear to be associated with a reduction in all-cause mortality in both primary and secondary prevention compared to those without an ICD despite a median time on the waiting list of only 8 months (estimated 1-year: 88±3% vs […]

Leave a Comment! Posted in Cardiac Transplantation Tags: , , , , , ,
July 8, 2013

Pulmonary rehabilitation in lung transplant candidates


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Although patients often participate in exercise training or rehabilitation prior to undergoing lung transplantation, the impact of pulmonary rehabilitation prior to lung transplantation has not been widely studied. This retrospective study described a pulmonary rehabilitation program designed for patients awaiting lung transplantation, assessed the exercise capacity, training volumes, and health related quality of life in […]

Leave a Comment! Posted in Lung Transplantation Tags: , , ,