July 10, 2013

A cardioprotective preservation strategy employing ex vivo heart perfusion facilitates successful transplant of donor hearts after cardiocirculatory death.


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Various techniques are being explored to optimize hearts and the assess organ function before transplantation. This may ultimately increase the number of organs available for transplantation. In this experimental model of DCD, an ex vivo heart perfusion strategy using initial reperfusion with a tepid adenosine-lidocaine cardioplegia and continuous myocardial perfusion minimized myocardial injury and improved short-term post-transplant function.

Cardiac Transplantation

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