April 14, 2012

A Cluster of Pneumocystis Infections Among Renal Transplant Recipients: Molecular Evidence of Colonized Patients as Potential Infectious Sources of Pneumocystis jirovecii.


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Kidney transplant recipients are usually receive prophylaxis for Pneumocystis infections for 6-12 months post-transplant. Although infections are generally uncommon, several outbreaks in transplant patients have been reported in the past two decades. In this study from France, 18 kidney transplant patients developed Pneumocystis infection. These patients were compared to control patients with Pneumocystis pneumonia. Molecular typing confirmed the role of colonization as a potential source of infection. Nosocomial sources must be considered when looking for a cause of Pneumocystis clusters.

Renal Transplantation, Transplant Infectious Disease

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