January 11, 2010

Asymmetrical Dimethylarginine Is Associated with Renal and Cardiovascular Outcomes and All-cause Mortality in Renal Transplant Recipients


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ADMA is a known risk factor for mortality and cardiovascular events in the CKD and ESRD populations. This study found that transplant recipients with higher levels of ADMA were at an increased risk of graft failure, cardiovascular events and death. Whether therapeutic interventions that lower ADMA levels would decrease the risk of death is unknown.

Renal Transplantation