Archive for the ‘Liver Transplantation’ Category

November 28, 2013

Outcomes of Simultaneous Liver and Kidney Transplantation in Relation to a High Level of Preformed Donor-Specific Antibodies


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Liver transplants rarely experience antibody-mediated rejection, and it has been suggested that a liver transplant can protect the kidney if a simultaneous transplant is performed. In this single-center study, patients who received a simultaneous liver-kidney transplant had a higher risk of acute rejection, but similar renal function and patient and graft survival, whether or not […]

No Comments Posted in Liver Transplantation, Renal Transplantation
October 25, 2013

Immunosuppression Regimen and the Risk of Acute Rejection in HIV-Infected Kidney Transplant Recipients

Renal transplantation for carefully selected HIV-positive patients has become well-accepted over the last decade. There remain concerns about the risk of overimmunosuppression in this group, due to their pre-existing immunodeficiency due to HIV infection. In this US registry study, HIV-positive patients actually had a higher risk of acute rejection than HIV-negative recipients, but this increased […]

No Comments Posted in Liver Transplantation, Renal Transplantation
June 21, 2013

Health-related quality of life and perceived need for mental health services in adolescent solid organ transplant recipients.


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The purpose of the following investigation was to assess interest in mental health services among parents of adolescent solid organ transplant recipients and the relationship between parent perceived need for mental health services and patient health-related quality of life (HRQOL). Sixty-three parents rated interest in receiving 10 mental health services, and patient HRQOL ratings were […]

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation
June 21, 2013

Is there an association between immunosuppressant therapy medication adherence and depression, quality of life, and personality traits in the kidney and liver transplant population?


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In the following study, researchers measured the association of transplant patients’ personality, depression, and quality of life with medication adherence in a cross-sectional group of kidney and liver transplant recipients greater than 1 year post-transplant.86 kidney and 50 liver transplant patients completed the surveys. Results found kidney transplant patients who exhibited “low openness” scores were […]

No Comments Posted in Liver Transplantation, Renal Transplantation
June 21, 2013

Care complexity, mood, and quality of life in liver pre-transplant patients.


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In the following study, researchers sought to document the frequency of care complexity in liver transplant candidates, and its association with mood disturbance and poor health-related quality of life (HRQoL). Patients from three European hospitals, were assessed for early bio-psychosocial health risks and needs (INTERMED tool), and with the Hospital Anxiety and Depression Scale (HADS). […]

No Comments Posted in Liver Transplantation
June 21, 2013

Simultaneous Thoracic and Abdominal Transplantation: Can We Justify Two Organs for One Recipient?


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This paper reviews the outcomes documented in the UNOS database for recipients of simulataneous thoracic and abdominal transplants. An interesting ethical discussion concludes the article.

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation
June 21, 2013

Special Issue: The American Society of Transplantation Infectious Diseases Guidelines 3rd Edition


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This supplement to the American Journal of Transplantation is dedicated to transplant infectious diseases. The articles in the supplement are guidelines for various pathogens and infectious syndromes that affect transplant recipients. This is the 3rd edition of the guidelines and updates the previous edition published in 2009. Three new chapters were added to this edition: […]

No Comments Posted in Cardiac Transplantation, Intestinal Transplantation, Liver Transplantation, Lung Transplantation, Pancreas Transplantation, Renal Transplantation, Transplant Infectious Disease
June 21, 2013

Randomized Controlled Trial of High-Dose Intradermal Versus Standard-Dose Intramuscular Influenza Vaccine in Organ Transplant Recipients


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Influenza vaccine is recommended for transplant recipients annually. There are several types of influenza vaccines on the market now including standard intramuscular, adjuvanted intramuscular and intradermal. An advantage of giving flu vaccine intradermally is to take advantage of the abundant Langerhans/dendritic cells at the site that act as potent antigen presenting cells. Baluch et al. […]

No Comments Posted in Cardiac Transplantation, Intestinal Transplantation, Liver Transplantation, Lung Transplantation, Pancreas Transplantation, Renal Transplantation, Transplant Infectious Disease
June 21, 2013

Optimal Testing of the Live Organ Donor for Blood-Borne Viral Pathogens: The Report of a Consensus Conference


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Transmission of infection from donor to recipient is an an inherent risk in transplantation that can likely never be completely eliminated. This is true even in living donation, where transmission of hepatitis C and HIV has been reported. This paper reports the results of a conference on this topic. Most significant is the fact that […]

No Comments Posted in Cardiac Transplantation, Intestinal Transplantation, Liver Transplantation, Lung Transplantation, Pancreas Transplantation, Renal Transplantation, Transplant Infectious Disease, Uncategorized
June 21, 2013

Transmission of Strongyloides stercoralis Through Transplantation of Solid Organs – Pennsylvania, 2012.


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Strongyloides is an intestinal nematode that is endemic in tropical areas. Most infected persons are asymptomatic. However, in immunocompromised, the infection can become disseminated and fatal. Infected organ donors can transmit Strongyloides to recipients and this has been described in the past. This report describes three organ recipients who were diagnosed with Strongyloides. Serum from […]

No Comments Posted in Liver Transplantation, Pancreas Transplantation, Renal Transplantation, Transplant Infectious Disease