Archive for the ‘Liver Transplantation’ Category

April 1, 2013

Impact of Consideration of Transplantation on End-of-Life Care for Patients During a Terminal Hospitalization


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The researchers of this study looked at how consideration of transplantation affects the end-of-life care received by patients. An evaluation of the care provided was undertaken by abstracting medical records for 496 adults who died in one transplant medical center between April 2005 and April 2006. The quality indicators measured were chosen from the Assessing […]

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation, Uncategorized
January 28, 2013

Quality of Life, Depression, and Psychosocial Characteristics of Patients Awaiting Liver Transplants


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The identification of the psychological issues that impair the quality of life and the adherence to treatment in transplant candidates are important. This study evaluated the presence of symptoms of depression and the quality of life of liver transplant candidates.One hundred liver transplant candidates underwent a psychological analysis the Short Form-36 (SF-36) Quality of Life […]

No Comments Posted in Liver Transplantation
January 28, 2013

Quality of Life, Depression, and Psychosocial Characteristics of Patients Awaiting Liver Transplants


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The identification of the psychological issues that impair the quality of life and the adherence to treatment in transplant candidates are important. This study evaluated the presence of symptoms of depression and the quality of life of liver transplant candidates.One hundred liver transplant candidates underwent a psychological analysis the Short Form-36 (SF-36) Quality of Life […]

No Comments Posted in Liver Transplantation
October 30, 2012

Tobacco Smoking and Solid Organ Transplantation

Smoking remains a major public health issue. This review article discuss the effects of smoking by both donors and recipients on outcomes after transplant. It also covers the literature on smoking cessation. They also argue whether active smoking should be a contraindication to transplantation.

No Comments Posted in Cardiac Transplantation, Intestinal Transplantation, Liver Transplantation, Lung Transplantation, Pancreas Transplantation, Renal Transplantation
October 30, 2012

Impact of expanded-criteria donors on patient survival after heart, lung, liver and combined organ transplantation


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A contemporary and Canadian perspective is presented on the outcomes following extended use donor criteria for solid organ transplant recipients. This Quebec based study analyzes outcomes in nonrenal organ groups.

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation
October 30, 2012

Calcineurin Inhibitor Sparing With Mycophenolate Mofetil in Liver Transplantion: A Systematic Review of Randomized Controlled Trials


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Chronic kidney disease is a significant complication after liver transplantation. A common strategy is to add mycophenolic acid (MPA) in order to reduce or eliminate calcineurin inhibitors (CnI). Although this is a common practice, the authors were only able to find 8 randomized controlled trials assessing its effects. Use of MPA does improve renal function, […]

No Comments Posted in Liver Transplantation, Renal Transplantation
September 19, 2012

The Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT): a new tool for the psychosocial evaluation of pre-transplant candidates.


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In this study, researchers developed and tested a new pre-transpalnt psychosocial assessment tool:the Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT). Five examiners blindly applied the SIPAT to 102 randomly selected transplant cases, including liver, heart, and lung patients. SIPAT scores were found to be highly predictive of the transplant psychosocial outcome. The authors concluded that […]

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Uncategorized
August 17, 2012

A Randomized, Controlled Study to Assess the Conversion From Calcineurin-Inhibitors to Everolimus After Liver Transplantation-PROTECT


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Post transplant inmunosuppression with calcineurin inhibitors (CNIs) is associated with renal dysfunction with an estimated rate of advanced CKD of 20% at 5 years. Everolimus is an mTOR inhibitors without the nephrotoxicity of CNIs. In this multicenter, prospective study, the authors evaluate the feasibility and effects of everolimus started at 30 days post liver transplant. […]

No Comments Posted in Liver Transplantation
August 17, 2012

Frequency, clinical presentation, and outcomes of drug-induced liver injury after liver transplantation.


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There is a lack of objective diagnostics test to confirm drug-induced liver injury. In this single-center study, the authors applied a specific criteria to identify the prevalence, clinical features and outcomes of drug-induced liver injury in a population of liver transplant recipients. The suspicion of drug-induced liver injury should be considered when unexplained allograft dysfunction […]

No Comments Posted in Liver Transplantation
August 17, 2012

Left Lobe Living Donor Liver Transplantation in Adults


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Left lobe living donor liver transplant (LL LDLT) has been associated with inferior graft survival due to smaller grafts. However, balancing the safety of donor and recipient is an integral part of LDLT. Several centers continue to use LL LDLT. In this aricle, the authors report a large scale study comparing outcomes of LL vs […]

No Comments Posted in Liver Transplantation