April 14, 2012

Chromosomally integrated human herpesvirus-6 in transplant recipients


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CIHHV-6 occurs in a small proportion of patients and presents with very high HHV-6 viral loads. It can be mistaken for active infection and unnecessarily treated. In this case series, 7 liver transplant patients with CIHHV-6 are described in addition to 14 cases already published in the literature. Although no patient had clinical symptoms related to HHV-6, five were treated due to high-level viremia. This paper brings awareness of an unusual presentation of HHV6 viremia that clinicians should be aware of when considering HHV6 as a potential cause of symptoms.

Transplant Infectious Disease

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