August 14, 2011

Current methodologies for detecting sensitization to HLA antigens


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This comprehensive review discusses the progression of tests used for HLA antibody detection over the last 40 years highlighting the limitations of each of the techniques. Much of the discussion is focused on the latest single antigen bead technology including its many advantages, listing of limitations relating to the technology and translation into accurate interpretation of results, and additional adaptations to current platforms to allow detection of complement-fixing antibodies. The reference format for this journal easily identifies articles of special interest and those of outstanding interest as they relate to the topic being referred.

 

Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation

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