April 14, 2012

Dengue virus infection in renal allograft recipients: a case series during 2010 outbreak.


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Dengue is a mosquito-transmitted disease endemic in South-East Asia. There are very few reports of Dengue infection post-organ transplant. This report describes 8 cases of dengue viral infection in renal transplant recipients, 3 of who developed severe disease with fatal hemorrhagic shock. Transplant patients need to be aware of personal-protection measures against mosquitos when travelling given the number of mosquito-transmitted illness for which there is no specific chemoprophylaxis or therapy (eg, Dengue, West Nile Virus etc.). In addition, clinicians should be aware that returning transplant travellers who are ill may have been exposed to these viruses.