October 30, 2012

Donor-Derived Fungal Infections in Organ Transplant Recipients: Guidelines of the American Society of Transplantation, Infectious Diseases Community of Practice


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Fungal infections including candida and mould infections are an important cause of morbidity and mortality in the post-transplant population. These guidelines of the American Society of Transplantation address the important issue of fungal transmission from donors. For example, donor-derived candidiasis can occur in kidney transplant recipients where preservative fluid contamination is a common source. This can lead to devastating consequences including arterial bleeds and allograft nephrectomy. There are also reports of donors who have unrecognized cryptococcal disease, histoplasmosis or coccidioidomycosis, all of which can be transmitted via the allograft. These are more common in donors from areas endemic for the fungal infection. The report highlights the evaluation of such donors and comments on the post-transplant management of recipients whose donors have suspected or proven infections.

Transplant Infectious Disease

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