July 9, 2012

Exercise training after lung transplantation improves participation in daily activity: a randomized controlled trial


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Best practice management of lung transplantation recipients includes both pre- and post-transplantation rehabilitation programs. However, the impact of a specific exercise intervention on recovery and post-transplant outcomes has not been rigorously studied. This randomized controlled trial studied the impact of a 3-month supervised exercise training program in lung transplant recipients with an uncomplicated post-transplant course. The program was initiated immediately following discharge from hospital. Treatment group patients exercised three times weekly for three months post-discharge. The primary endpoint was daily walking time, with other markers of daily physical activity, fitness, quality of life, self-perceived health status, and incidence of comorbidities studied as secondary endpoints. Although a high percentage of eligible patients refused to participate (almost 40%), of the randomized patients, the exercise intervention group had improved functional status and reduced cardiovascular morbidity in the first year post transplant.

Lung Transplantation

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