November 1, 2010

Five-Year Safety and Efficacy of Belatacept in Renal Transplantation


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Belatacept is the first costimulation blocker to be assessed in renal transplantation. Its mechanism of action is different from other immunosuppressive medications, and has been evaluated as a primary immunosuppressive agent in place of cyclosporine. This paper is an observational study extending the follow-up of the original randomized controlled trial. Although belatacept must be given intravenously on a monthly basis, it was well-accepted by patients, well-tolerated, and provided stable graft function over time.

Free full text kindly provided by the American Society of Nephrology

Renal Transplantation