October 18, 2009

H-Y Incompatibility Predicts Short-Term Outcomes for Kidney Transplant


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A recent registry analysis suggested that female recipients of a male kidney are an increased risk for graft loss. The putative mechanism was the minor histocompatibility antigen H-Y. This study repeated this analysis in a different registry. It found a slightly higher risk of graft loss for
female recipients of male kidneys at 1 year, but no difference at 10 years. The mechanisms responsible for this difference are unknown. 

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Renal Transplantation