April 1, 2013

Health-Related Quality of Life and Long-Term Survival and Graft Failure in Kidney Transplantation: A 12-Year Follow-Up Study


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Long-term survival for kidney transplant continues to show variability. This study examined whether health-related quality of life (HRQOL) predicts long-term mortality in kidney transplantation after adjustment for known risk factors.
A cohort of 347 kidney transplant recipients was followed up for 12 years after enrolment. They completed measures of HRQOL and medical records were reviewed to document clinical and cardiovascular risk factors and comorbidities at study entry 8 years after transplantation). The primary outcomes were ensuing all-cause mortality and all-cause graft failure. Results demonstrated physical HRQOL predicts long-term mortality and graft failure independently of sociodemographic and clinical risk factors in renal transplant patients.

Renal Transplantation

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