July 9, 2012

Hypoalbuminemia and early mortality after lung transplantation: a cohort study


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Hypoalbuminemia is frequently associated with morbidity and mortality in illness and aging patients. This study used Cox proportional hazard models to examine associations between serum albumin and rate of death after lung transplantation in 6808 adult patients with interstitial lung disease, COPD, or cystic fibrosis. Hypoalbuminemia was independently associated with increased risk of death in the first year after lung transplantation, particularly in patients with COPD or cystic fibrosis. Severe hypoalbuminemia had posttransplant adjusted mortality rate ratio of 1.35 (95% CI: 1.12-1.62)

Lung Transplantation

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