Immunosuppression Regimen and the Risk of Acute Rejection in HIV-Infected Kidney Transplant Recipients
Renal transplantation for carefully selected HIV-positive patients has become well-accepted over the last decade. There remain concerns about the risk of overimmunosuppression in this group, due to their pre-existing immunodeficiency due to HIV infection. In this US registry study, HIV-positive patients actually had a higher risk of acute rejection than HIV-negative recipients, but this increased risk was obviated by the use of thymoglobulin induction. These results should be considered when transplanting HIV-positive patients.