July 9, 2012

Impact of warm ischemia time on survival after heart transplantation


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Donor organ availability remains the limiting step in heart transplantation. Careful organ harvesting techniques aim to reduce organ damage and promote graft survival and adequate organ function post transplant. Donor organ damage occurs primarily as a result of ischemia-warm and cold phases-times and hypothermia. In this retrospective analysis, the authors reviewed the outcomes for warm ischemia time at a single heart transplant center. Their experience suggests reduced heart transplant recipient survival with increasing WIT (> 80 minutes) and that donor age was the most significant variable in increasing the risk of transplant recipient mortality. As for the author’s claim regarding potential implications in heart transplantation from donor hearts procured after circulatory death (DCD), further in-depth investigations will be required.

Cardiac Transplantation

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