June 21, 2013

Is there an association between immunosuppressant therapy medication adherence and depression, quality of life, and personality traits in the kidney and liver transplant population?


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In the following study, researchers measured the association of transplant patients’ personality, depression, and quality of life with medication adherence in a cross-sectional group of kidney and liver transplant recipients greater than 1 year post-transplant.86 kidney and 50 liver transplant patients completed the surveys. Results found kidney transplant patients who exhibited “low openness” scores were 91% more likely to be nonadherent, and physical functional status was strongly associated with nonadherence. In the liver sample, age was associated with adherence. For every year increase in age, adherence increased by 7%. The research results suggest a link between degree of patient openness as a personality trait to physical functional status and depression in kidney transplant population.

Liver Transplantation, Renal Transplantation

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