July 9, 2012

Outcomes of Children Following a First Hospitalization for Dilated Cardiomyopathy


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This is a single center analysis of 83 pediatric patients with dilated cardiomyopathy who had their first hospitalization between 2004 and 2009. Of these patients 6% died and 18% were transplanted during their first hospitalization. Of the 71 remaining, 15% died and 38% had undergone transplantation by 1 year following this hospitalization. The overall freedom from death, transplantation, or re-hospitalization at one year following admission was 21%. Factors identified as risk factors for death or transplantation at one year after initial presentation included fractional shortening, left ventricular ejection fraction, serum cholesterol, uric acid, mixed venous saturation, and atrial filling pressures at the time of the initial presentation. This study suggests that first hospitalization for DCM is a warning sign for future deterioration and suggest close follow-up and consideration for earlier transplant listing.

Cardiac Transplantation

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