February 23, 2012

Outcomes of renal transplants from centers for disease control and prevention high-risk donors with prospective recipient viral testing: a single-center experience.


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The use of CDC-criteria high-risk donors in transplantation is controversial.  The use of pre-transplant nucleic acid amplification testing (NAT) for HCV and HIV reduces the window period for these infections.  There are limited data on follow-up of patients that receive organs from high-risk donors.  In this single-center study, 50 patients received kidney transplants from high-risk donors.  Follow-up serology detected no seroconversions.  Although this is a relatively small study, it demonstrates that organs from high-risk donors who have negative NAT tests for HCV and HIV can be used and may shorten wait times.

Transplant Infectious Disease

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