June 21, 2013

Phospholipase A2 Receptor (PLA2R) Staining Is Useful in the Determination of De Novo Versus Recurrent Membranous Glomerulopathy


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The phospholipiase A2 receptor (PLA2R) has been identified as an important target in most cases of native membranous nephropathy. Distinguishing between post-transplant recurrent membranous nephropathy and de novo disease is important, In this paper, staining of renal transplant biopsies for PLA2R was found in cases with recurrent, but not de novo disease. This shows that de novo membranous nephropathy has a different etiology than recurrent disease.

Renal Transplantation

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