April 14, 2012

Pre-operative risk factors and clinical outcomes associated with vasoplegia in recipients of orthotopic heart transplantation in the contemporary era.


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Vasoplegia in this study was defined as persistent low systemic vascular resistance (<800 dyne/s/cm5 for more than 2 consecutive readings) despite multiple (≥2) intravenous pressor drugs at high dose (epinephrine ≥4 ug/min, norepinephrine ≥4 ug/min, dopamine ≥5 ug/kg/min, vasopressin ≥1 U/h) with preserved cardiac index (>2.5) between 6 and 48 hours after surgery.  Amiodarone use was not found to be a factor in the development of vasoplegia syndrome post heart transplant.

Cardiac Transplantation

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