February 23, 2012

Risk Factors, Clinical Features, and Outcomes of Toxoplasmosis in Solid-Organ Transplant Recipients: A Matched Case-Control Study.


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Toxoplasmosis is a relatively uncommon infectious complication after transplant.  Seropositive heart transplant recipients or heart transplant recipients who receive toxoplasmosis seropositive hearts generally receive lifelong prophylaxis.  A review of SOTs done in Spain identified 22 cases of toxoplasmosis.  Although the majority of these were heart transplant recipients, kidney and liver transplant patients also developed the disease.  Most of this was primary infection rather than reactivation.  Being seronegative for toxoplasmosis prior to transplant was an independent risk factor for developing toxoplasmosis.  This study provides new insights about toxoplasmosis in organ transplant recipients.

Transplant Infectious Disease

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