October 30, 2012

SaLUTaRy: Survey of lung transplant rejection


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Discrepancies in the interpretation of lung allograft biopsies by pathologists and pulmonologists prompted the International Society for Heart and Lung Transplantation to develop guidelines for interpretation, most recently updated in 2007. This study surveyed pathologists and pulmonologists in lung transplant centres in the United States to determine the interpretation and application of these guidelines. Of the respondents, 92% pathologists and 73% pulmonologists use the most recent 2007 updated guidelines, with the remainder using the 1996 version. Eighty percent of surveyed centres perform surveillance biopsies, although with no consistent timing. Substantial discrepancies persisted amongst pathologists and pulmonologists in the interpretation and subsequent treatment of allograft rejection.

Lung Transplantation

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