September 10, 2013

Should Eligibility for Heart Transplantation Be a Requirement for Left Ventricular Assist Device Use? Recommendations Based on a Systematic Review


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This Canadian group has generated the first systematic review of the clinical and economic effects of continuous-flow LVADs in Bridge to Transplant (BTT) and Destination Therapy (DT) patients. They conclude that evidence is sufficient to support LVAD use, regardless of transplantation eligibility status, as long as patients are carefully selected and program infrastructure and budget are adequate. Information gaps are identified and adoption of a Canadian-specific device registry is suggested.

Cardiac Transplantation

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