June 21, 2013

Subclinical Epstein_Barr Virus Viremia Among Adult Renal Transplant Recipients: Incidence and Consequences


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EBV viremia occurs frequently after transplantation and can be related to post-transplant lymphoproliferative disorders (PTLD). However, the consequences of the majority of viremia are unclear. Barnoulid et al. followed EBV viral loads in 383 kidney transplant patients during the first year post-transplant. 40% of patients had at least one detected viremia; viremia was more common in EBV mismatched patients and those that received ATG. While these risk factors for EBV are well known, the authors also found that EBV infection was associated with opportunistic infection and graft loss. This study adds to our knowledge on EBV although further work is necessary to determine what to do with patients who had chronic low level viremia.

Renal Transplantation, Transplant Infectious Disease

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