November 28, 2013
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ACE-I inhibitors and ARBs are first-line treatment for patients with glomerular renal diseases, such as diabetes mellitus. Their role in transplantation is not as clear-cut, since the major renal histologic changes are primarily interstitial and vascular. Randomized controlled trials have not found a benefit in renal graft survival with RAS blockade but two small RCTs […]
November 26, 2012
This is part of the recently published KDIGO guidelines for blood pressure management. As opposed to other sections of these guidelines, the authors recommend a target blood pressure < 130/80 for all patients regardless of degree of proteinuria. No specific class of antihypertensive agent is preferred in these guidelines.
December 19, 2011
The use of antihypertensive agents varies from center to center. This article provides further support for the routine use of ACE inhibitors as first-line agents in heart transplant recipients for additional renal protective and hemodynamic benefits.