Posts Tagged ‘acute cellular rejection’

August 2, 2013

Urinary-Cell mRNA Profile and Acute Cellular Rejection in Kidney Allografts


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The gold standard fro diagnosing acute rejection remains biopsy. A non-invasive test that could reliably diagnose rejection would be an important step forward. In this study, a set of three different RNA molecules in the urine of renal transplant recipients showed a high degree of sensitivity for acute cellular rejection, and distinguished it from antibody-mediated […]

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August 14, 2011

Pathologic Interpretation of Transbronchial Biopsy for Acute Rejection of Lung Allograft is Highly Variable


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Acute cellular rejection is typically diagnosed by histopathologic examination of transbronchial lung biopsies.  Pathologic grading of acute rejection has been standardized, however interobserver variability for the grading has not been adequately determined. A blinded panel of pathologists regraded 1566 biopsies from 845 lung transplant recipients enrolled in the Lung Allograft Rejection Gene Expression Observational study.  […]

No Comments Posted in Lung Transplantation