Posts Tagged ‘Adherence’

September 26, 2013

Improving Outcomes of Renal Transplant Recipients With Behavioral Adherence Contracts: A Randomized Controlled Trial


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Non-adherence is a well-recognized cause of poor outcomes post-transplant, but effective interventions to address this problem have been rare. In this randomized controlled trial, patients who were at least one year post-transplant and developed an adherence contract with a pharmacist had better medication adherence, as measured by prescription refills. The rate of hospitalizations was also […]

No Comments Posted in Renal Transplantation, Uncategorized
August 30, 2013

Improving Outcomes of Renal Transplant Recipients With Behavioral Adherence Contracts: A Randomized Controlled Trial


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Non-adherence is a well-recognized risk factor for adverse events post-transplant, but there have been few interventions aimed at improving adherence. In this randomized controlled trial, regular interaction with a pharmacist and a contract laying out behaviours required of the patient improved adherence, as measured by medication refills. It also resulted in fewer hospitalization.

No Comments Posted in Renal Transplantation, Uncategorized
June 21, 2013

Is there an association between immunosuppressant therapy medication adherence and depression, quality of life, and personality traits in the kidney and liver transplant population?


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In the following study, researchers measured the association of transplant patients’ personality, depression, and quality of life with medication adherence in a cross-sectional group of kidney and liver transplant recipients greater than 1 year post-transplant.86 kidney and 50 liver transplant patients completed the surveys. Results found kidney transplant patients who exhibited “low openness” scores were […]

No Comments Posted in Liver Transplantation, Renal Transplantation
January 28, 2013

Quality of Life, Depression, and Psychosocial Characteristics of Patients Awaiting Liver Transplants


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The identification of the psychological issues that impair the quality of life and the adherence to treatment in transplant candidates are important. This study evaluated the presence of symptoms of depression and the quality of life of liver transplant candidates.One hundred liver transplant candidates underwent a psychological analysis the Short Form-36 (SF-36) Quality of Life […]

No Comments Posted in Liver Transplantation
January 28, 2013

Quality of Life, Depression, and Psychosocial Characteristics of Patients Awaiting Liver Transplants


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The identification of the psychological issues that impair the quality of life and the adherence to treatment in transplant candidates are important. This study evaluated the presence of symptoms of depression and the quality of life of liver transplant candidates.One hundred liver transplant candidates underwent a psychological analysis the Short Form-36 (SF-36) Quality of Life […]

No Comments Posted in Liver Transplantation
November 18, 2011

Adherence to Immunosuppression in Adult Lung Transplant Recipients: Prevalence and Risk Factors


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Adherence to medications has not been well studied in lung transplant recipients.  Using a Medication Event Monitoring System, tacrolimus intake was prospectively monitored in 91 lung transplant recipients for a median of 95 days.  Medication adherence was 92.3%.  14% of patients had one or two drug holidays.  Non-adherent patients tended to be younger and with […]

No Comments Posted in Lung Transplantation
October 1, 2011

The spectrum of nonadherence with medication in heart, liver, and lung transplant patients assessed in various ways


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In order to ascertain methodological gaps in assessing adherence in the literature this prospective study of adult organ transplant recipients compared 79 heart, 55 liver, and 104 lung recipients . Non-adherence was measured using self-report, collateral report, blood assays, electronic monitoring, and their combinations. In the overall sample, depending on the method used, Non-adherence ranged […]

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation
October 1, 2011

Medical adherence in pediatric organ transplantation: what are the next steps?


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There is a growing body of research on the high rates and negative consequences of non-adherence after transplantation. This article reviews the current literature on medication and regimen adherence after transplantation with the goal of identifying gaps in the literature, as well as suggestions for future research. The authors highlight the current knowledge but emphasize […]

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation
July 4, 2011

Nonadherent behaviors after solid organ transplantation.


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This study surveyed 218 solid organ transplant recipients: 103 liver, 50 kidney, 52 heart, and 13 lung (152 men; mean  age was 52.2 ± 0.8 years; mean time from transplantation, 83.6 ± 4.5 months). They found 37.9%, 38.8%, and 12.8% of patients reported nonadherence to immunosuppressive therapy, to correct lifestyle, and to medical prescriptions. Among […]

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation