Posts Tagged ‘antibodies’

August 31, 2013

Higher Risk of Kidney Graft Failure in the Presence of Anti-Angiotensin II Type-1 Receptor Antibodies


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While HLA antibodies are a well-recognized risk factor for graft loss, the role of non-HLA antibodies is less clear. Antibodies to angiotensin II type I receptor has been previously reported in patients with failing grafts. In this study, patients who developed anti-AT I receptor antibodies had a higher risk of graft failure over and above […]

No Comments Posted in Renal Transplantation, Uncategorized
February 23, 2012

Influenza Vaccination in the Organ Transplant Recipient: Review and Summary Recommendations

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Annual influenza vaccination is recommended for organ transplant patients although the different types of influenza vaccines and timing of vaccination can be a source of confusion for the provider.  This review summarizes the current state of knowledge for annual influenza vaccination the organ transplant recipient.  It discusses the various studies done in the transplant population […]

No Comments Posted in Transplant Infectious Disease
August 14, 2011

Desensitization in HLA-Incompatible Kidney Recipients and Survival

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Sensitization to HLA antigens results in increased waiting times for a transplant, which is associated with an increased risk of death. The current study examined whether performing living-donor renal transplants following desensitization resulted in a survival benefit when compared to equally sensitized patients on the wait list. A protocol using plasmapheresis and low-dose IVIg was […]

No Comments Posted in Renal Transplantation
June 18, 2011

Antibody Response After a Single Dose of an AS03-Adjuvanted Split-Virion Influenza A (H1N1) Vaccine in Heart Transplant Recipients

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Pandemic influenza caused a wide spectrum of disease in organ transplant recipients.    Monovalent adjuvanted H1N1 vaccine became available in Canada and Europe whereas a nonadjuvanted formulation was available in the U.S.  This European study showed that only one-third of the vaccinated cohort had seroprotective titers to vaccine.  These results are similar to other studies presented […]

No Comments Posted in Transplant Infectious Disease