Posts Tagged ‘ARB’

January 28, 2013

Angiotensin II Blockade in Kidney Transplant Recipients


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ACE-inhibitors and ARBs are a mainstay of treatment for patients with glomerular renal disease or proteinuria. In this randomized controlled trial, patients receiving a renal transplant were randomized to losartan or placebo. There was no difference in the primary endpoint, which was a composite of doubling of interstitial fibrosis on renal biopsy at five years […]

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January 28, 2013

Angiotensin II Blockade in Kidney Transplant Recipients


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ACE-inhibitors and ARBs are a mainstay of treatment for patients with glomerular renal disease or proteinuria. In this randomized controlled trial, patients receiving a renal transplant were randomized to losartan or placebo. There was no difference in the primary endpoint, which was a composite of doubling of interstitial fibrosis on renal biopsy at five years […]

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November 18, 2011

Treatment of Kidney Transplant Recipients With ACEi/ARB and Risk of Respiratory Tract Cancer: A Collaborative Transplant Study Report


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Meta-analyses in the general population have suggested that ACE-inhibitors and angiotensin receptor blockers may increase the risk of cancer, particularly lung cancer. In this report from the international Collaborative Transplant Study, use of ACE-I or ARB as associated with a statistically significant increased risk of lung cancer, but only in patients with a smoking history. […]

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