Posts Tagged ‘biopsy’

September 1, 2013

Podocyte Effacement Closely Links to suPAR Levels at Time of Posttransplantation Focal Segmental Glomerulosclerosis Occurrence and Improves With Therapy


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Serum soluble urokinase-type plasminogen activator receptor (suPAR) has been put forth as the a candidate for the elusive “FSGS” factor that may lead to aggressive and early recurrence post-transplant. This study of patients with recurrent FSGS post-transplant found higher suPAR levels in patients with more extensive podocyte damage on renal biopsy. However, this study is […]

No Comments Posted in Renal Transplantation
June 21, 2013

Phospholipase A2 Receptor (PLA2R) Staining Is Useful in the Determination of De Novo Versus Recurrent Membranous Glomerulopathy


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

The phospholipiase A2 receptor (PLA2R) has been identified as an important target in most cases of native membranous nephropathy. Distinguishing between post-transplant recurrent membranous nephropathy and de novo disease is important, In this paper, staining of renal transplant biopsies for PLA2R was found in cases with recurrent, but not de novo disease. This shows that […]

No Comments Posted in Renal Transplantation
January 28, 2013

Angiotensin II Blockade in Kidney Transplant Recipients


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

ACE-inhibitors and ARBs are a mainstay of treatment for patients with glomerular renal disease or proteinuria. In this randomized controlled trial, patients receiving a renal transplant were randomized to losartan or placebo. There was no difference in the primary endpoint, which was a composite of doubling of interstitial fibrosis on renal biopsy at five years […]

No Comments Posted in Renal Transplantation
January 28, 2013

Predicting acute cardiac rejection from donor heart and pre-transplant recipient blood gene expression


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Perhaps one of the most intriguing concepts in modern medicine is the potential for personalized approaches to medical therapy. Currently, there are no biomarkers in clinical use that can predict, before transplantation, the occurrence of acute rejection. This Canadian group of researchers originating from the PROOF centre in British Columbia has identified a biomarker panel […]

No Comments Posted in Cardiac Transplantation
January 28, 2013

Angiotensin II Blockade in Kidney Transplant Recipients


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

ACE-inhibitors and ARBs are a mainstay of treatment for patients with glomerular renal disease or proteinuria. In this randomized controlled trial, patients receiving a renal transplant were randomized to losartan or placebo. There was no difference in the primary endpoint, which was a composite of doubling of interstitial fibrosis on renal biopsy at five years […]

No Comments Posted in Renal Transplantation
January 28, 2013

Predicting acute cardiac rejection from donor heart and pre-transplant recipient blood gene expression


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Perhaps one of the most intriguing concepts in modern medicine is the potential for personalized approaches to medical therapy. Currently, there are no biomarkers in clinical use that can predict, before transplantation, the occurrence of acute rejection. This Canadian group of researchers originating from the PROOF centre in British Columbia has identified a biomarker panel […]

No Comments Posted in Cardiac Transplantation
July 4, 2011

The ISHLT working formulation for pathologic diagnosis of antibody-mediated rejection in heart transplantation: Evolution and current status (2005-2011)


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Antibody mediated rejection (AMR) was a focus of the ISHLT 2011 Annual Conference. This Consensus paper reviews several technical issues, discusses nomenclature and proposes a new grading system to allow for standardization in the classification and diagnosis of AMR.

No Comments Posted in Cardiac Transplantation