Posts Tagged ‘bone disease’

June 21, 2013

Oral Paricalcitol Reduces the Prevalence of Posttransplant Hyperparathyroidism: Results of an Open Label Randomized Trial


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Bone disease and secondary hyperparathyroidism are common following renal transplantation. This open-label randomized controlled trial compared the calcitriol analog paricalcitol to placebo, with a primary endpoint of hyperparathyroidism at one year post-transplant. There was less hyperparathyroidism in the paricalcitol-treated group. However, there was no difference in bone density between groups. Also, these patients were not […]

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October 30, 2012

A 1-Year Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Ibandronate on Bone Loss Following Renal Transplantation


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Bone disease post-transplant is a common problem, related to pre-transplant bone disease as well as immunosuppression. This randomized controlled trial assessed the effect of adding IV ibandronate to a regimen of calcium and calcitriol in patients post-renal transplant. Surprisingly, there was no benefit on bone density in the lumbar spine compared to the control group, […]

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