Posts Tagged ‘calcineurin inhibitor’

October 30, 2012

Calcineurin Inhibitor Sparing With Mycophenolate Mofetil in Liver Transplantion: A Systematic Review of Randomized Controlled Trials


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Chronic kidney disease is a significant complication after liver transplantation. A common strategy is to add mycophenolic acid (MPA) in order to reduce or eliminate calcineurin inhibitors (CnI). Although this is a common practice, the authors were only able to find 8 randomized controlled trials assessing its effects. Use of MPA does improve renal function, […]

No Comments Posted in Liver Transplantation, Renal Transplantation
April 14, 2012

PRKCB is associated with calcineurin inhibitor-induced renal dysfunction in heart transplant recipients.


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This Canadian study further expands the knowledge on potential biomarkers of calcineurin inhibitor induced nephrotoxicity and may play a future role in developing personalized immunosuppression profiles for individual heart transplant recipients.

No Comments Posted in Cardiac Transplantation