Posts Tagged ‘CDC’

November 18, 2011

Novel C1q assay reveals a clinically relevant subset of HLA antibodies independent of immunoglobulin G strength on single antigen beads


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The first pre-transplant cross-matches were performed using complement-dependent cytotoxicity (CDC) and showed immediate clinical benefits. Current HLA antibody test methods rely on Luminex single antigen bead (SAB) technology allowing for the sensitive identification of multiple DSAs even in highly sensitized patients. However, the clinical relevance of the HLA antibodies identified by the Luminex platform remains […]

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