Posts Tagged ‘cellular rejection’

June 21, 2013

Correlation of circulating donor-specific anti-HLA antibodies and presence of C4d in endomyocardial biopsy with heart allograft outcomes: A single-center, retrospective study.


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Approximately 10 – 20% of heart transplant recipients will develop AMR. Standardized nomenclature has improved the diagnosis. This single center study revisits the risks of Class I and II DSA to C4D +IF and graft failure. C4d staining correlated better with graft failure in patients with DSA to only Class I or DSA to both […]

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November 26, 2012

Intentional ABO-incompatible heart transplantation: A case report of 2 adult patients.


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Although ABO incompatible transplantation is accepted within the pediatric population, there have been few attempts in adults. This group from Sweden, accepted patients with anti-A or anti-B antibody titer≤1:8 for ABO-incompatible heart transplantation without any special pre-treatment and patients with antibody titers of IgG 1:16 and 1:32, provided 1 apheresis session could be performed immediately […]

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December 19, 2011

Impact of virtual cross match on waiting times for heart transplantation


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The concept of virtual crossmatching has been adopted by the cardiac transplant community and has expanded the donor pool by its feasibility.  In contrast, prospective cross matches which required donor cells and approximately 4 hours to perform limited the donor pool to regional centers where recipient blood could be sent.  Within Canada, the use of […]

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