Posts Tagged ‘cholesterol’

December 19, 2011

Influence of Metabolic Syndrome on Development of Cardiac Allograft Vasculopathy in the Transplanted Heart


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This study explores the hypothesis that patients with metabolic syndrome would develop more cardiac allograft vasculopathy (CAV) as a consequence of the endothelial dysfunction associated with this syndrome. The authors analyzed the relationship between the presence of metabolic syndrome at the time of heart transplantation and in the first 3 months with the development of […]

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November 18, 2011

Safety and efficacy of early aggressive versus cholesterol-driven lipid-lowering strategies in heart transplantation: A pilot, randomized, intravascular ultrasound study


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The safety and efficacy of pravastatin, simvastatin and atorvastatin in heart transplant recipients have been tested in several single-center studies. This study demonstrated that a titrated-dosing approach of fluvastatin is as effective as a maximal early dose in achieving target LDL levels at 1year post transplant. The maximal-dosing approach seems to provide additional benefit by […]

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