Posts Tagged ‘Corticosteroids’

July 4, 2011

A prospective, randomized trial of single-drug versus dual-drug immunosuppression in heart transplantation: the tacrolimus in combination, tacrolimus alone compared (TICTAC) trial


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The TICTAC trial is the first prospective test of single-drug versus dual-drug maintenance immunosuppression in heart transplantation. Rapid steroid tapering was successful in all study patients. Three-year survival and low rates of allograft rejection and vasculopathy were observed in both arms (either TAC monotherapy or TAC/MMF), supporting the efficacy of either regimen along with a […]

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