Posts Tagged ‘deceased donation’

June 21, 2013

Renal Transplantation After Ex Vivo Normothermic Perfusion: The First Clinical Study


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The standard method of kidney preservation uses an acellular solution at low temperatures, either cold storage or with machine perfusion. This article describes an system which adapts cardioplumonary bypass technology to perfuse the kidney with a oxygenated blood prior to implantation. In this uncontrolled study, kidneys that underwent ex vivo normothermic perfusion had a low […]

No Comments Posted in Renal Transplantation
July 9, 2012

Arguments against promoting organ transplants from brain-dead donors, and views of contemporary Japanese on life and death


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A revision of Japan’s Organ Transplant Law in 2009 led to an ethical debate on the differences in definitions of death, age requirements for donors, requirements for brain-death determination and organ extraction, and the appropriateness of priority transplants for relatives. Many hoped the revised law would permit transplants in Japan according to global standards. However, […]

No Comments Posted in Cardiac Transplantation, Intestinal Transplantation, Liver Transplantation, Lung Transplantation, Pancreas Transplantation, Renal Transplantation
July 9, 2012

The Case for Kidney Donation Before End-of-Life Care

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This article, and the 6 open peer commentaries that accompany it, discusses whether ante mortem donation of kidneys is ethically feasible in those patients in whom a decision has been made to discontinue life sustaining therapy. The authors argue that this strategy is ethically equivalent to donation after cardiac death, since the ante mortem removal […]

No Comments Posted in Renal Transplantation
February 23, 2012

Outcomes of renal transplants from centers for disease control and prevention high-risk donors with prospective recipient viral testing: a single-center experience.


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The use of CDC-criteria high-risk donors in transplantation is controversial.  The use of pre-transplant nucleic acid amplification testing (NAT) for HCV and HIV reduces the window period for these infections.  There are limited data on follow-up of patients that receive organs from high-risk donors.  In this single-center study, 50 patients received kidney transplants from high-risk […]

No Comments Posted in Transplant Infectious Disease
November 18, 2011

Better off living–the ethics of the new UNOS proposal for allocating kidneys for transplantation

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This article, part of CJASN’s new section on public policy, critically analyzes the new policy proposal by UNOS to allocate deceased donors kidneys in the UNOS.  The authors examine several potential objections: 1. Is waiting time a fair way to rank order patients since there are disparities in gaining access to listing? 2. It is […]

No Comments Posted in Renal Transplantation
November 18, 2011

Potential Limitations of Presumed Consent Legislation

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Presumed consent (PC) legislation has been touted as a potential solution to the disparity between supply and demand for deceased donor organs.  This study examines the legislation in European countries with and without presumed consent legislation and reports on interviews with senior transplant physicians in these countries.  The authors conclude that there are multiple country-specific, […]

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation
June 18, 2011

New organ transplant policies in Japan, including the family-oriented priority donation clause.

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The author outlines the recent changes to Japanese law and transplant policy that allow for organ procurement after brain death with only family consent (previously there had to also be prior written consent from the donor). As well, the new Japanese law allows donors to prioritize family members to receive their organs after brain death, […]

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation