Posts Tagged ‘endomyocardial biopsy’

June 21, 2013

Correlation of circulating donor-specific anti-HLA antibodies and presence of C4d in endomyocardial biopsy with heart allograft outcomes: A single-center, retrospective study.


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Approximately 10 – 20% of heart transplant recipients will develop AMR. Standardized nomenclature has improved the diagnosis. This single center study revisits the risks of Class I and II DSA to C4D +IF and graft failure. C4d staining correlated better with graft failure in patients with DSA to only Class I or DSA to both […]

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November 26, 2012

Intentional ABO-incompatible heart transplantation: A case report of 2 adult patients.


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Although ABO incompatible transplantation is accepted within the pediatric population, there have been few attempts in adults. This group from Sweden, accepted patients with anti-A or anti-B antibody titer≤1:8 for ABO-incompatible heart transplantation without any special pre-treatment and patients with antibody titers of IgG 1:16 and 1:32, provided 1 apheresis session could be performed immediately […]

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February 23, 2012

A longitudinal study of the course of asymptomatic antibody-mediated rejection in heart transplantation


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Recent studies directly linked asymptomatic AMR with a higher risk of cardiac allograft vasculopathy and mortality.  The study provides insight on the incidence of asymptomatic AMR early and late after transplantation. The course of untreated asymptomatic AMR appears to be influenced by the severity of its initial presentation and, to a lesser extent, the time […]

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