Posts Tagged ‘fibrosis’

December 19, 2011

Hepatic Steatosis at 1 Year is an Additional Predictor of Subsequent Fibrosis Severity in Liver Transplant Recipients with Recurrent Hepatitis C Virus


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Recurrence of HCV post liver transplantation is universal, and clinically significant recurrence can have a major impact on both patient and graft survival. Prediction of patients that will go on to significant recurrence allow for both close follow up and consideration for anti-viral therapy. The present study shows that steatosis in the early post liver […]

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November 18, 2011

Limiting Hepatitis C Virus Progression in Liver Transplant Recipients Using Sirolimus-Based Immunosuppression


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Hepatitis C recurrence following liver transplantation is universal, and it is one of the main reasons for inferior outcomes in this population. Sirolimus, which has antifibrotic properties, reduces progression of liver fibrosis in animal models. In this single-centre, retrospective study, liver transplant recipients initially treated with sirolimus showed less progression of fibrosis on surveillance biopsies […]

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