Posts Tagged ‘graft vasculopathy’

April 1, 2013

Donor-Specific Antibodies to Class II Antigens Are Associated With Accelerated Cardiac Allograft Vasculopathy: A Three-Dimensional Volumetric Intravascular Ultrasound Study.


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This preliminary study from Mayo clinic demonstrated that cardiac transplant patients with preformed class II DSA may be at increased risk for accelerated graft vasculopathy on consecutive 3D IVUS. Although this technology may not be available at all centers, this sstudy provides further weight to the potential clinical impact of class II DSA.

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November 18, 2011

Safety and efficacy of early aggressive versus cholesterol-driven lipid-lowering strategies in heart transplantation: A pilot, randomized, intravascular ultrasound study


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The safety and efficacy of pravastatin, simvastatin and atorvastatin in heart transplant recipients have been tested in several single-center studies. This study demonstrated that a titrated-dosing approach of fluvastatin is as effective as a maximal early dose in achieving target LDL levels at 1year post transplant. The maximal-dosing approach seems to provide additional benefit by […]

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