Posts Tagged ‘Luminex’

January 28, 2013

Consensus Guidelines on the Testing and Clinical Management Issues Associated With HLA and Non-HLA Antibodies in Transplantation


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Solid phase assays on the Luminex platform have become the standard for the detection and characterization of HLA antibodies. However, transplant professionals have struggled with interpretation of the highly sensitive Luminex assay with respect to cytotoxicity assays and clinical relevance. To tackle this problem The Transplantation Society asked a group of experts with extensive experience […]

No Comments Posted in Cardiac Transplantation, Intestinal Transplantation, Lung Transplantation, Pancreas Transplantation, Renal Transplantation
January 28, 2013

Consensus Guidelines on the Testing and Clinical Management Issues Associated With HLA and Non-HLA Antibodies in Transplantation


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Solid phase assays on the Luminex platform have become the standard for the detection and characterization of HLA antibodies. However, transplant professionals have struggled with interpretation of the highly sensitive Luminex assay with respect to cytotoxicity assays and clinical relevance. To tackle this problem The Transplantation Society asked a group of experts with extensive experience […]

No Comments Posted in Cardiac Transplantation, Intestinal Transplantation, Lung Transplantation, Pancreas Transplantation, Renal Transplantation
November 18, 2011

Novel C1q assay reveals a clinically relevant subset of HLA antibodies independent of immunoglobulin G strength on single antigen beads


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The first pre-transplant cross-matches were performed using complement-dependent cytotoxicity (CDC) and showed immediate clinical benefits. Current HLA antibody test methods rely on Luminex single antigen bead (SAB) technology allowing for the sensitive identification of multiple DSAs even in highly sensitized patients. However, the clinical relevance of the HLA antibodies identified by the Luminex platform remains […]

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation