Posts Tagged ‘mechanical circulatory support’

January 28, 2013

Medical and psychosocial predictors of mechanical circulatory support device implantation and competing outcomes in the Waiting for a New Heart Study


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Medical and psychosocial factors are related to 1-year outcomes in the Waiting for a New Heart Study. With increased use of mechanical circulatory support devices (MCSD) over the course of the study, this study evaluated variables as predictors of MCSD in an extended follow-up.Variables assessed at time of listing included psychosocial risk (depression, social isolation), […]

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January 28, 2013

Statement Regarding the Pre and Post Market Assessment of Durable, Implantable Ventricular Assist Devices in the United States: Executive Summary: Endorsed by The Society of Thoracic Surgeons, American Association for Thoracic Surgery, American Heart Association, Heart Failure Society of America, International Society for Heart and Lung Transplantation, and the Interagency Registry of Mechanically Assisted Circulatory Support.


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A panel of experts convened to discuss topics relevant to promoting an environment of safe and effective introduction of new technologies for mechanical cirulatory support. The focus of this Statement Paper includes : (1) innovative clinical trial designs; (2) the need for a new encompassing indication for therapy to facilitate device evaluation and reduce disparities […]

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January 28, 2013

Morbidity and Mortality in Heart Transplant Candidates Supported with Mechanical Circulatory Support. Is Reappraisal of the Current UNOS Thoracic Organ Allocation Policy Justified?


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Within the cardiac transplant community there has been much discussion regarding the evolution in technology of mechanical circulatory support and the impact on organ allocation. This article published in Circulation suggests transplant candidates supported with contemporary continuous flow LVADs have favorable waiting list outcomes. In contrast outcomes worsen significantly once a serious LVAD-related complication occurs. […]

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January 28, 2013

Medical and psychosocial predictors of mechanical circulatory support device implantation and competing outcomes in the Waiting for a New Heart Study


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Medical and psychosocial factors are related to 1-year outcomes in the Waiting for a New Heart Study. With increased use of mechanical circulatory support devices (MCSD) over the course of the study, this study evaluated variables as predictors of MCSD in an extended follow-up.Variables assessed at time of listing included psychosocial risk (depression, social isolation), […]

No Comments Posted in Cardiac Transplantation
November 26, 2012

Recommendations for the Use of Mechanical Circulatory Support: Device Strategies and Patient Selection: A Scientific Statement From the American Heart Association.


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This recently e-published Scientific Statement from the AHA, reviews current published international guidelines, patient selection, clinical indications, risk scores and complications.

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October 30, 2012

Can Long-Term Ventricular Assist Devices Be Safely Implanted in Low-Volume Non-Heart Transplant Centres?


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The development of MCS programs capable of implanting long-term VADs at non-transplant centres may provide more Canadians suffering from end-stage heart failure and critical cardiogenic shock with access to cardiac transplantation as a life-saving therapy. The ongoing debate regarding center volume and outcomes is addressed.

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September 19, 2012

Quality of Life and Left Ventricular Assist Device Support


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This thorough literature review describes current indicators of quality of life in ventricular assist device patients and addresses cognitive function, sleep disturbance, emotional distress, sexual activity and end of life issues. A “must read” for mechanical circulatory support team members.

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April 14, 2012

Survival benefit of implantable cardioverter-defibrillators in left ventricular assist device-supported heart failure patients.


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Several studies have shown significant rates of ventricular tachyarrhythmia events while on VAD support, ranging from 22% -52%.  This single center study noted the mean time to first shock after LVAD implant was 129 ± 109 days, the LVAD cohort was more likely to have an appropriate ICD before LVAD implant than after and a survival […]

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April 14, 2012

The Fourth INTERMACS Annual Report: 4,000 implants and counting.


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The Annual Report is now available for review and summarizes the registry’s first 5 years of data collection on mechanical circulatory support recipients.

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December 19, 2011

Usefulness of Two-Dimensional Echocardiographic Parameters of the Left Side of the Heart to Predict Right Ventricular Failure After Left Ventricular Assist Device Implantation


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Right ventricular failure (RVF) following left ventricular assist device (LVAD) implantation can be a challenging if not catastrophic event.  The risk assessment strategies for right ventricular failure vary in complexity. This article by Mancini et al, demonstrates that the preoperativeLVechocardiographic RVF score, focusing on only left-sided parameters could accurately predict the development of RVF after […]

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