Posts Tagged ‘mortality’

September 9, 2013

Is it time for a cardiac allocation score? First results from the Eurotransplant pilot study on a survival benefit based heart allocation

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The Eurotransplant group demonstrated mortality on the waitlist could be predicted for non-VAD critically ill (high urgency or urgent request) patients using the Heart Failure Survival Score (HFSS) and the Seattle Heart Failure Model (SHFM). The Index for Mortality Prediction After Cardiac Transplantation (IMPACT) score was successful for predicting mortality post transplant in non-VAD patients. […]

No Comments Posted in Cardiac Transplantation
July 9, 2013

Prophylactic implantable cardioverter defibrillator treatment in patients with end-stage heart failure awaiting heart transplantation.


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This observational study supports the CCS recommendations of ICD consideration in transplant eligible patients. In this study, ICDs appear to be associated with a reduction in all-cause mortality in both primary and secondary prevention compared to those without an ICD despite a median time on the waiting list of only 8 months (estimated 1-year: 88±3% vs […]

No Comments Posted in Cardiac Transplantation
June 21, 2013

Everolimus Versus Mycophenolate Mofetil in Heart Transplantation: A Randomized, Multicenter Trial.

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This multicenter, randomized controlled trial assessed the efficacy, safety and incidence of CAV in de novo heart transplant patients receiving everolimus at two doses (1.5 mg/day or 3.0 mg/day in divided doses) with reduced-dose cyclosporine versus MMF with full-dose cyclosporine. The high dose everolimus group was terminated due to increased mortality. The lower dose everolimus […]

No Comments Posted in Cardiac Transplantation
April 1, 2013

Health-Related Quality of Life and Long-Term Survival and Graft Failure in Kidney Transplantation: A 12-Year Follow-Up Study


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Long-term survival for kidney transplant continues to show variability. This study examined whether health-related quality of life (HRQOL) predicts long-term mortality in kidney transplantation after adjustment for known risk factors. A cohort of 347 kidney transplant recipients was followed up for 12 years after enrolment. They completed measures of HRQOL and medical records were reviewed […]

No Comments Posted in Renal Transplantation
January 28, 2013

Epidemiology, Clinical Characteristics and Outcomes of Extensively Drug-Resistant Acinetobacter baumannii Infections among Solid Organ Transplant Recipients.


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Acinetobacter is an important nosocomial pathogen. Extensively drug resistant Acinetobacter is generally only sensitive to colistin and tigecycline. The authors performed a retrospective study of SOT recipients over a 5 year period, that were colonized or infected with extensively drug resistant Acinetobacter to determine outcomes. 69 patients were included, most of whom had ventilator-associated pneumonia. […]

No Comments Posted in Transplant Infectious Disease
January 28, 2013

Epidemiology, Clinical Characteristics and Outcomes of Extensively Drug-Resistant Acinetobacter baumannii Infections among Solid Organ Transplant Recipients.

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Acinetobacter is an important nosocomial pathogen. Extensively drug resistant Acinetobacter is generally only sensitive to colistin and tigecycline. The authors performed a retrospective study of SOT recipients over a 5 year period, that were colonized or infected with extensively drug resistant Acinetobacter to determine outcomes. 69 patients were included, most of whom had ventilator-associated pneumonia. […]

No Comments Posted in Transplant Infectious Disease
December 19, 2011

Association of Pretransplant Serum Phosphorus with Posttransplant Outcomes

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Both hypo- and hyperphosphatemia are associated with an increased risk of death in dialysis patients. In this large registry study, severe hyperphosphatemia was associated with increased risk of death. More moderate hyperphosphatemia was associated with graft failure after kidney transplantation. This shows the importance of phosphate management in patients pre-transplant, as it will affect post-transplant […]

No Comments Posted in Renal Transplantation
June 14, 2011

Elevated Fibroblast Growth Factor 23 is a Risk Factor for Kidney Transplant Loss and Mortality

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Fibroblast growth factor 23 (FGF 23) is a protein that is elevated in CKD and ESRD and is associated with increased risk of cardiovascular disease and death. In this single-center study, higher FGF 23 levels in a group of stable renal transplant patients were associated with a greater risk of mortality and graft failure. Whether […]

No Comments Posted in Renal Transplantation