Posts Tagged ‘normothermic perfusion’

December 19, 2011

Superior Preservation of DCD Livers With Continuous Normothermic Perfusion


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Donation after cardiac death (DCD) liver transplantation has grown because of the discrepancy between the number of patients on the transplant waiting list and the number of available organs. Unfortunately, numerous studies have demonstrated increased biliary complications and lower graft survival with DCD liver transplants. Multiple groups are looking at the use of machine perfusion […]

No Comments Posted in Liver Transplantation
August 14, 2011

Normothermic Ex Vivo Lung Perfusion in Clinical Lung Transplantation


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Low usage of lungs from multi-organ donors has prompted researchers to pursue innovative strategies for allowing transplantation of non-optimal lungs.  One such innovation is ex vivo lung perfusion with the use of acellular normothermic perfusate after retrieval, allowing assessment of lung viability prior to implantation.  This prospective, nonrandomized clinical trial examined primary graft dysfunction in […]

No Comments Posted in Lung Transplantation
August 14, 2011

Hepatic Steatosis and Normothermic Perfusion—Preliminary Experiments in a Porcine Model


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Machine preservation in liver transplantation is widely use in several centers that study animal models. Normothermic preservation has been showing to have advantages over hypothermic preservation. This article report successful results using normothermic preservation in steatotic grafts and the potential clinical use in expanded criteria donor grafts.

No Comments Posted in Liver Transplantation