Posts Tagged ‘outcomes’

September 26, 2013

Improving Outcomes of Renal Transplant Recipients With Behavioral Adherence Contracts: A Randomized Controlled Trial


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Non-adherence is a well-recognized cause of poor outcomes post-transplant, but effective interventions to address this problem have been rare. In this randomized controlled trial, patients who were at least one year post-transplant and developed an adherence contract with a pharmacist had better medication adherence, as measured by prescription refills. The rate of hospitalizations was also […]

No Comments Posted in Renal Transplantation, Uncategorized
August 30, 2013

Improving Outcomes of Renal Transplant Recipients With Behavioral Adherence Contracts: A Randomized Controlled Trial


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Non-adherence is a well-recognized risk factor for adverse events post-transplant, but there have been few interventions aimed at improving adherence. In this randomized controlled trial, regular interaction with a pharmacist and a contract laying out behaviours required of the patient improved adherence, as measured by medication refills. It also resulted in fewer hospitalization.

No Comments Posted in Renal Transplantation, Uncategorized
June 21, 2013

Advanced Therapies for Congenital Heart Disease: Ventricular Assist Devices and Heart Transplantation.


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This article reviews heart transplant and mechanical circulatory support approaches and outcomes in the management of congenital heart disease; a growing demographic in the adult heart transplant community.

No Comments Posted in Cardiac Transplantation
June 21, 2013

Everolimus immunosuppression in de novo heart transplant recipients: What does the evidence tell us now?


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This review article analyzes the currently available data supporting the use of everolimus in de novo heart transplant patients. Rejection, renal function, malignancy, infection and wound complications including pleural and pericardial effusions are examined. The evidence suggests that the most convincing reasons for use of everolimus are to slow the progression of CAV and to […]

No Comments Posted in Cardiac Transplantation
June 21, 2013

Simultaneous Thoracic and Abdominal Transplantation: Can We Justify Two Organs for One Recipient?


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This paper reviews the outcomes documented in the UNOS database for recipients of simulataneous thoracic and abdominal transplants. An interesting ethical discussion concludes the article.

No Comments Posted in Cardiac Transplantation, Liver Transplantation, Lung Transplantation, Renal Transplantation
June 21, 2013

Long-term outcome in patients treated with combined heart and liver transplantation for familial amyloidotic cardiomyopathy


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Currently, adults with congenital heart disease account for 3% of heart and nearly 40% of heart_lung transplant recipients worldwide. Ten years of patient outcomes were reviewed between 2001 and 2011. This single center, high volume center demonstrated comparable early and mid-term outcomes in adult congenital heart patients to general outcomes when careful recipient selection was […]

No Comments Posted in Cardiac Transplantation
June 21, 2013

Clinical outcomes after ventricular assist device implantation in adults with complex congenital heart disease.


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This single center case series from the Texas Heart Institute describes the clinical challanges and outcomes of 6 patients with complex CHD who underwent VAD implantation with a variety of devices. A future article (epub) is pending in the same journal (JHLT) which may provide further insight into this challenging patient population: Heart transplantation for […]

No Comments Posted in Cardiac Transplantation
April 1, 2013

OPTN/SRTR 2011 Annual Data Report: heart.


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This annual report from the Organ Procurement and Transplantation Network provides an American update with temporal trends in cardiac transplant activity.

No Comments Posted in Cardiac Transplantation
April 1, 2013

Fifth INTERMACS annual report: Risk factor analysis from more than 6,000 mechanical circulatory support patients.


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The 5th annual report of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) summarizes and analyzes the first 6 years of patient and data collection. The current analysis includes more than 6000 patients and updated risk factors for continuous flow pumps. Among continuous flow pumps, actuarial survival is 80% at 1 year and 70% […]

No Comments Posted in Cardiac Transplantation
January 28, 2013

Transplantation With Kidneys Retrieved From Deceased Donors With Acute Renal Failure


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While acute renal failure or acute kidney injury (AKI) is reversible, it is often seen as a contraindication to transplantation. This retrospective, single-center study compared both standard and expanded criteria donor kidney with and without AKI. Although the rates of delayed graft function were higher in the kidneys with AKI, 1-year results were similar for […]

No Comments Posted in Renal Transplantation