Posts Tagged ‘pancreas transplant’

September 26, 2013

Acute Cellular and Antibody-Mediated Rejection of the Pancreas Allograft: Incidence, Risk Factors and Outcomes

Antibody-mediated pancreas transplant rejection is a relatively recently recognized entity. In this retrospective study, the rate of antibody-mediated rejection post-pancreas transplant was similar to that of acute cellular rejection. Class I DSA were more predictive of antibody-mediated rejection than class II DSA. Antibody-mediated rejection should be considered in all patients with pancreas graft dysfunction post-transplant.

No Comments Posted in Pancreas Transplantation, Renal Transplantation
January 28, 2013

Pancreas-After-Kidney Versus Synchronous Pancreas-Kidney Transplantation: Comparison of Intermediate-Term Results


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Most registries show worse outcomes with pancreas-after-kidney (PAK) compared to simultaneous pancreas-kidney (SPK) transplants. In this single-centre, retrospective study, living donor renal transplants followed by pancreas transplants showed comparable results to SPK, despite the long time between kidney and pancreas transplants. Greater use of PAK may shorten time of dialysis for patient with a living […]

No Comments Posted in Pancreas Transplantation, Renal Transplantation
January 28, 2013

Pancreas-After-Kidney Versus Synchronous Pancreas-Kidney Transplantation: Comparison of Intermediate-Term Results


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Most registries show worse outcomes with pancreas-after-kidney (PAK) compared to simultaneous pancreas-kidney (SPK) transplants. In this single-centre, retrospective study, living donor renal transplants followed by pancreas transplants showed comparable results to SPK, despite the long time between kidney and pancreas transplants. Greater use of PAK may shorten time of dialysis for patient with a living […]

No Comments Posted in Pancreas Transplantation, Renal Transplantation
November 18, 2011

Guidelines for the diagnosis of antibody-mediated rejection in pancreas allografts-updated Banff grading schema


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

The Banff consensus, originally developed as a histopathological guideline to diagnoses in transplanted kidneys, has been adopted by other transplanted organs. Pancreas transplant specialists developed and implemented their first set of guidelines in 2008 with much of the detail pertaining to T-cell-mediated rejection. This latest set of guidelines now addresses the criteria proposed for the […]

No Comments Posted in Uncategorized
August 14, 2011

The Impact of Pancreas Transplantation on Kidney Allograft Survival


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Pancreas-after-kidney (PAK) transplantation optimizes the use of living-donor kidneys and addresses the problems of both type I diabetes and end-stage renal disease. However, there are concerns about requiring patients to undergo two operations, as well as the impact that the more intense immunosuppression early post-pancreas transplant may have on renal allograft function. This registry study […]

No Comments Posted in Renal Transplantation
June 17, 2011

Outcomes of Simultaneous Pancreas-Kidney Transplantation in Type 2 Diabetic Recipients


Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177

Warning: Invalid argument supplied for foreach() in /nfs/c04/h03/mnt/65750/domains/transplantnow.com/html/wp-content/themes/nephrology/scripts/pubmed.php on line 177
.   .   

Pancreas transplantation has traditionally been reserved for patients with type I diabetes, due to the belief that the insulin resistance seen in type II diabetes would not allow patients to come off exogenous insulin. In this analysis of US registry day, 9% of kidney-pancreas transplants went to patients with type II diabetes, and rates of […]

No Comments Posted in Renal Transplantation