Posts Tagged ‘predictor’

January 28, 2013

Predicting acute cardiac rejection from donor heart and pre-transplant recipient blood gene expression


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Perhaps one of the most intriguing concepts in modern medicine is the potential for personalized approaches to medical therapy. Currently, there are no biomarkers in clinical use that can predict, before transplantation, the occurrence of acute rejection. This Canadian group of researchers originating from the PROOF centre in British Columbia has identified a biomarker panel […]

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January 28, 2013

Predicting acute cardiac rejection from donor heart and pre-transplant recipient blood gene expression


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Perhaps one of the most intriguing concepts in modern medicine is the potential for personalized approaches to medical therapy. Currently, there are no biomarkers in clinical use that can predict, before transplantation, the occurrence of acute rejection. This Canadian group of researchers originating from the PROOF centre in British Columbia has identified a biomarker panel […]

No Comments Posted in Cardiac Transplantation
May 23, 2012

Influence of donor and recipient sex mismatch on heart transplant outcomes: Analysis of the International Society for Heart and Lung Transplantation Registry.


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The limited number of donor organs demands careful donor/recipient matching in heart transplantation. Using the International Society for Heart and Lung Transplantation (ISHLT) Registry, this publication explored the associations between donor and recipient sex in overall survival, death-censored allograft survival, AR, and CAV. The ISHLT Registry is the largest repository of heart transplant outcomes worldwide. […]

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April 14, 2012

PRKCB is associated with calcineurin inhibitor-induced renal dysfunction in heart transplant recipients.


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This Canadian study further expands the knowledge on potential biomarkers of calcineurin inhibitor induced nephrotoxicity and may play a future role in developing personalized immunosuppression profiles for individual heart transplant recipients.

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