Posts Tagged ‘prophylaxis’

October 30, 2012

Emergence of Aspergillus calidoustus Infection in the Era of Posttransplantation Azole Prophylaxis.


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Invasive aspergillosis is an important cause of morbidity after lung transplant. The majority of lung transplant centers use universal anti-mould prophylaxis for 3-6 months after transplant. This may be extended further depending on the patient’s level of immunosuppression. Resistant fungi can emerge with such prolonged prophylaxis. This paper reports a series of lung transplant patients […]

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February 23, 2012

Clinical utility of molecular surveillance for cytomegalovirus after antiviral prophylaxis in high-risk solid organ transplant recipients.


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Late CMV disease is common after the discontinuation of prophylaxis especially in the high-risk CMV D+/R- group.  Transplant centers take various approaches to detect CMV disease and these include prolonging prophylaxis, doing weekly CMV viral load monitoring, or observing for symptoms.  In this single-center review, 71 high-risk patients received 3 months of antiviral prophylaxis followed […]

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February 23, 2012

Risk Factors, Clinical Features, and Outcomes of Toxoplasmosis in Solid-Organ Transplant Recipients: A Matched Case-Control Study.


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Toxoplasmosis is a relatively uncommon infectious complication after transplant.  Seropositive heart transplant recipients or heart transplant recipients who receive toxoplasmosis seropositive hearts generally receive lifelong prophylaxis.  A review of SOTs done in Spain identified 22 cases of toxoplasmosis.  Although the majority of these were heart transplant recipients, kidney and liver transplant patients also developed the […]

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